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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Expert Rev Neurother. 2020 Sep 2;20(11):1109–1121. doi: 10.1080/14737175.2020.1807330

Table 2:

Plant extract effects on Mn intoxication in animal models

Phytomedicines Class Molecular structure Manganese protective
effects
Experimental
model
Silymarin (Silybum marianum) Flavonoid graphic file with name nihms-1621687-t0002.jpg Nephroprotection Decreased lipid peroxidation Antioxidant [152] Rat
Boldine (Peumus boldus) Alkaloid graphic file with name nihms-1621687-t0003.jpg Partially improved locomotor dysfunction and TBARS levels [135] Drosophila melanogaster