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. Author manuscript; available in PMC: 2021 Nov 15.
Published in final edited form as: J Immunol. 2020 Oct 7;205(10):2821–2833. doi: 10.4049/jimmunol.2000652

Fig. 7. Summary of HLH phenotype in mice with varied treatments.

Fig. 7.

Six or five hallmarks were assessed in CpG-treated or other inflammatory stimuli-treated mice, respectively, in accordance with the HLH-2004 diagnostic criteria. An H-score ≥169 accurately classifies 90% of individuals and corresponds to a sensitivity of 93% and specificity of 86% for HLH diagnosis. NS, not significant = P > 0.05; + = P < 0.05; ++ = P < 0.01; +++ = P < 0.001; ++++ P < 0.0001; ND, not determined.