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. Author manuscript; available in PMC: 2021 Nov 10.
Published in final edited form as: Circulation. 2020 Sep 15;142(19):1848–1862. doi: 10.1161/CIRCULATIONAHA.119.041433

Figure 5. Sex differences in tissue-specific EC gene expression.

Figure 5.

(A) Projections of ECs from brain, heart, and lung onto t-SNE maps color-coded by sex. (B) List of genes differentially expressed between male and female ECs in each organ. (C) KEGG pathway enrichment analysis of sex- and organ-specific DEGs show correlation of sex-dependent genes in ECs with organ-specific disease and/or cellular pathways.