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. 2020 Nov 11;7:384. doi: 10.1038/s41597-020-00727-4

Table 1.

Transforms initially chosen from existing LHASA knowledgebase.

ID Name Ring Forming
1031 Paal-Knorr Pyrrole Synthesis Yes
1039 Feist Synthesis of Pyrroles Yes
1171 Hantzsch Thiazole Synthesis Yes
1391 Allene 2 + 2 Cycloaddition Yes
1439 Pyrazoles from Beta Carbonyl Carboxylic Acid Derivatives Yes
2201 Fused Arylpyridines via o-Aminocarbonyls Yes
2218 Tetrazoles from Azide and Nitriles Yes
2230 Phthalazin-1-ones from 2-Acylbenzoic Acids Yes
2238 Fused Aryl(2,3-H/R)Pyridines (Pictet-Spengler) Yes
2267 Sonogashira Coupling No
2269 Kabbe Synthesis of 4-Chromanones Yes
2630 Benzazepin-2-ones by Pictet-Spengler Reaction Yes
2684 Benzo[b]furans from 2-Hydroxyphenyl Acetylenes Yes