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. 2020 Oct 29;8:571677. doi: 10.3389/fcell.2020.571677

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Copyright © 2020 Cheaito, Bahmad, Jalloul, Hadadeh, Msheik, El-Hajj, Mukherji, Al-Sayegh and Abou-Kheir.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enrichment maps of pathways enriched in upregulated genes (red) and downregulated genes (blue) in AUB-PrC cells vs. tissues. Enrichment maps of pathways among prostate unaffected (A) and tumor (B) samples were built using EnrichmentMap analysis on Cytoscape 3.7.2 software. Each node (circle) represents a distinct pathway (red representing upregulated pathways and blue representing downregulated pathways), and edges (lines) represent the number of genes overlapping between two pathways, determined using the similarity coefficient.