TABLE 2.
Patient # | Cell lines | Gleason score | ISUP grade group | Immunofluorescent staining relative to unaffected cells |
mRNA expression of different prostate epithelial lineage and stem cell markers relative to unaffected cells |
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CK8 | CK5 | VIM | CDH1 | CDH2 | CK8 | CK18 | NKX3.1 | AR | p63 | CD34 | ||||
Patient 1 | AUB-PrC-U1 and AUB-PrC-T1 | 9(5 + 4) | Grade group 5 | ↑ | ↑ | ↓ | ↑ | ↓ | ↓ | ↓ | ↑ | ↑ | ↑ | ↑ |
Patient 2 | AUB-PrC-U2 and AUB-PrC-T2 | 7(4 + 3) | Grade group 3 | ↑ | ↑ | ↑ | ↑ | ↑ | ↑ | ↑ | ↑ | ↓ | ↑ | ↑ |
Patient 3 | AUB-PrC-U3 and AUB-PrC-T3 | 7(3 + 4) | Grade group 2 | ↑ | ↑ | ↓ | ↓ | ↑ | ↓ | ↑ | ↑ | ↑ | ↓ | ↓ |
Patient 4 | AUB-PrC-U4 and AUB-PrC-T4 | 6(3 + 3) | Grade group 1 | ↑ | ↑ | ↑ | – | – | – | – | – | – | – | – |
Patient 5 | AUB–PrC-U5 and AUB-PrC-T5 | 7(4 + 3) | Grade group 3 | ↑ | ↑ | ↑ | – | – | – | – | – | – | – | – |
Patient 6 | AUB-PrC-U6 and AUB-PrC-T6 | 7(3 + 4) | Grade group 2 | ↑ | ↑ | ↓ | – | – | – | – | – | – | – | – |
Patient 7 | AUB-PrC-U7 and AUB-PrC-T7 | 7(4 + 3) | Grade group 3 | ↑ | ↑ | ↑ | – | – | – | – | – | – | – | – |
AUB-PrC, American University of Beirut-Prostate Cells; ISUP, International Society of Urological Pathology; ↑, increased; ↓, decreased.