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. 2020 Nov 11;11(11):965. doi: 10.1038/s41419-020-03183-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A Timeline for the development of quercetin-treated human oocytes and early embryos up to the blastocyst stage. B Improved Pb1 extrusion of human embryos after quercetin treatment from GV oocytes. C Improved Pb1 extrusion of human embryos after quercetin treatment from GVBD oocytes. D Improved fertility rate, blastocyst formation rate, and high-quality blastocysts rate of human embryos after quercetin treatment. E Morphology of embryos after in vitro culture with or without quercetin in the culture medium. Scale bar, 25 μm. P < 0.05 vs. control as calculated by two-tailed unpaired Student’s t-tests.