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. 2020 Oct 29;8:544311. doi: 10.3389/fbioe.2020.544311

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Copyright © 2020 Byrne, Bonnier, Efeoglu, Moore and McIntyre.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(I) Loadings of PC1 for pairwise analysis of cytoplasm of PS-NH₂ exposed cells with the control for 10 μM (red), 5 μM (blue), and 2.5 μM (black) after 8 h exposure. (II) Comparison of the Loading of PC1s for different (2.5 μM) PS-NH₂ exposure times (cytoplasm). 4, 8, 12, 24, and 48 h are indicated with black, blue, green, red, and magenta, respectively. The dotted line represents the zero ‘0’ point for each loading. Loadings are offset for clarity. Positive features of the PCs are related to exposed cells while negative features of the PCs are related to their controls (Efeoglu et al., 2016).