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(A) Diagram illustrating biomimetic peptide/acryloyl-bisphosphonate (Ac-BP) conjugation and hMSCs seeding on 2D titanium substrates, (B) osseointegration in the site of the implantation with the biomimetic peptide/Ac-BP conjugated titanium screws in rabbit tibiae/femurs (in vivo). (C) And the reaction of biomimetic peptide conjugation to TiO2 substrates with Ac-BP.
