FIGURE 1.

Differential microbiota diversity profiling in mGlu5 KO mice. (A) Alpha diversity metrics including Observed, Shannon, Inverse Simpson (InvSimpson), and Fisher indices. There was no difference in all four indices between WT and mGlu5 KO mice (Kruskal–Wallis test). Beta diversity principal coordinate analysis of WT and mGlu5 KO data using (B) Bray-Curtis distance and (C) unweighted UniFrac distances. The samples were clustered according to the genotype, and there were significant differences between the two genotypes in both Bray-Curtis and unweighted UniFrac distances. Permutation multivariate ANOVA is (n = 6) for both WT and mGlu5 KO mice groups).