Table 1.
Demographic and group statistics of participants with isolated RBD, prodromal RBD, and other disorders with motor activity during sleep
| (1) iRBD | (2) Prodromal RBD | (3) Other* | p** | ||||
|---|---|---|---|---|---|---|---|
| N = 40 | N = 18 | N = 64 | Group | 1 vs. 2 | 1 vs. 3 | 2 vs. 3 | |
| Age, y | 67.0 (14.0) | 55.5 (10.0) | 58.5 (16.0) | 0.0014 | 0.0247 | 0.0022 | 1.0000 |
| Sex, female | 6 (15.0%) | 3 (16.7%) | 19 (29.7%) | 0.1785 | 1.0000 | 0.2532 | 0.7433 |
| REM duration, minutes | 72.3 (44.0) | 72.0 (25.5) | 75.0 (52.5) | 0.8033 | 1.0000 | 1.0000 | 1.0000 |
| PLMS index | 25.4 (33.9) | 22.3 (34.6) | 15.1 (27.1) | 0.0771 | 0.8329 | 0.0712 | 1.0000 |
| Apnea-hypopnea index | 6.9 (10.0) | 19.9 (17.8) | 11.4 (23.0) | 0.0247 | 0.0497 | 0.0820 | 1.0000 |
| PAP therapy | 17 (42.5%) | 2 (11.1%) | 14 (21.9%) | 0.0187 | 0.0395 | 0.0653 | 1.0000 |
| Antidepressant therapy | 21 (52.5%) | 4 (22.2%) | 14 (21.9%) | 0.0033 | 0.0682 | 0.0035 | 1.0000 |
Age, REM duration, PLMS index, and apnea–hypopnea index are summarized by median values and interquartile ranges. Sex, PAP therapy, and antidepressant therapy are provided as absolute numbers and percentages. Group differences were assessed, as appropriate, by Kruskal–Wallis and Pearson’s χ 2 tests. Statistically significant differences between groups after Bonferroni-Holm correction are shown as bold values. iRBD, isolated REM sleep behavior disorder; REM, rapid eye movement; RWA, REM sleep without atonia; PLMS, periodic limb movements during sleep; PAP, positive airways pressure.
*Sleep apnea (n = 11), PLMS (n = 4), sleep apnea with PLMS (n = 44), and other (n = 5).
**Bonferroni–Holm corrected.