Fig. 4.

Schematic representation of the simulated metabolism of C. autoethanogenum and C. kluyveri under chemostat cultivation conditions. In CO/H₂ experiments, CO feed rate = 4.8 mmol l⁻¹ h⁻¹; growth rate = 0.021 h⁻¹ and working volume = 1 l. In CO/AC conditions, CO feed rate = 6.4 mmol l⁻¹ h⁻¹; growth rate = 0.028 h⁻¹ and working volume = 0.75 l. Blue arrows indicate the fluxes direction. Metabolites colored green are extracellular metabolites, partly exchanged between species and partly excreted or assimilated to/from the media. The heatmap on the right shows the fluxes of the R$\#$ reactions selected on the map for all conditions. Flux values are log transformed (log(Flux + 1)) for a better visualization. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)