Table 1.
Intended outcome | Potential for engineered gene drive to spread and persist | |||
---|---|---|---|---|
Self‐limiting | Self‐sustaining | |||
High threshold | Low threshold | High threshold | Low threshold | |
Population suppression or modification | Spatially restricted (localised) and temporally restricted (transient) drives | Spatially unrestricted (non‐localised) and temporally restricted (transient) drives | Spatially restricted (localised) and temporally unrestricted (persistent) drives | Spatially and temporally unrestricted (non‐localised and persistent) drives |