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. 2020 Nov 12;18(11):e06297. doi: 10.2903/j.efsa.2020.6297

Table 1.

Possible dimensions to categorise engineered gene drive strategies

Intended outcome Potential for engineered gene drive to spread and persist
Self‐limiting Self‐sustaining
High threshold Low threshold High threshold Low threshold
Population suppression or modification Spatially restricted (localised) and temporally restricted (transient) drives Spatially unrestricted (non‐localised) and temporally restricted (transient) drives Spatially restricted (localised) and temporally unrestricted (persistent) drives Spatially and temporally unrestricted (non‐localised and persistent) drives