Table 2. Pharmacogenetics analysis and Hardy-Weinberg equilibrium.
Gene | Variation | Genotype | Frequency | % | P valuea |
---|---|---|---|---|---|
ABCB1 | rs1045642 | A/A | 2 | 16.67 | 0.0543 |
A/G | 2 | 16.67 | |||
G/G | 8 | 66.66 | |||
ABCC4 | rs1751034 | C/C | 1 | 8.33 | 0.9768 |
C/T | 5 | 41.67 | |||
T/T | 6 | 50.00 | |||
ABCC8 | rs757110 | A/A | 5 | 41.67 | 0.7003 |
A/C | 5 | 41.67 | |||
C/C | 2 | 16.66 | |||
ABCG2 | rs2231142 | G/G | 6 | 50.00 | 0.3865 |
G/T | 4 | 33.33 | |||
T/T | 2 | 16.67 | |||
CYP2C9 | *1/*1 | 11 | 91.67 | – | |
*3/c.820-6326A>C | 1 | 8.33 | |||
CYP2C19 | *1/*1 | 4 | 33.33 | – | |
*1/*2 | 6 | 50.00 | |||
*2/*2 | 2 | 16.67 | |||
CYP3A4 | *1A/*1A | 5 | 41.67 | – | |
*1A/*1G | 5 | 41.67 | |||
*1A/*18B | 1 | 8.33 | |||
*1G/*1G | 1 | 8.33 | |||
CYP3A5 | *1/*1 | 2 | 16.66 | – | |
*1/*3 | 5 | 41.67 | |||
*3/*3 | 5 | 41.67 | |||
CYP4F2 | *1/*1 | 7 | 58.33 | – | |
*1/*3 | 5 | 41.67 | |||
UGT1A1 | *1/*1 | 4 | 33.33 | – | |
*1/*6 | 5 | 41.67 | |||
*28/*80 | 3 | 25.00 | |||
UGT1A8 | rs1042597 | C/C | 2 | 16.67 | 0.9212 |
C/G | 6 | 50.00 | |||
G/G | 4 | 33.33 | |||
UGT2B15 | rs1902023 | A/A | 4 | 33.33 | 0.2482 |
A/C | 4 | 33.33 | |||
C/C | 4 | 33.33 |
a, Pearson chi-squared test.