Table 4. Initial dosage recommendation of tacrolimus in paediatric liver transplant.

Body weight (kg)	Dosage recommendationb	Genotypea			Drug combination
		CYP3A5*1	CYP3A5*3/*3		Without WZ	With WZ
5–17	0.10 mg/kg/day		Yes		Yes
17–60	0.05 mg/kg/day
5–10	0.25 mg/kg/day	Yes			Yes
10–17	0.20 mg/kg/day
17–36	0.15 mg/kg/day
36–60	0.10 mg/kg/day
5–11	0.10 mg/kg/day		Yes			Yes
11–60	0.05 mg/kg/day
5–10	0.20 mg/kg/day	Yes				Yes
10–22	0.15 mg/kg/day
22–60	0.10 mg/kg/day

^a, recipient; ^b, splited into two doses; CYP3A5*1, CYP3A5*1/*1 and CYP3A5*1/*3; WZ, wuzhi-capsule.