Summary of patient characteristics
| Characteristics | Patients with COVID-19 with Acute CVE (n = 6) | Patients with COVID-19 without Acute CVE (n = 99) | P value |
|---|---|---|---|
| Mean age (yr) | 62 ± 14 | 66 ± 17 | 0.41a |
| < 50 yrs, n (%) | 1 (17) | 14 (14) | >0.99b |
| ≥ 50 yrs, n (%) | 5 (83) | 85 (86) | |
| Sex, n (%) | 0.40b | ||
| Male | 5 (83) | 57 (58) | |
| Female | 1 (17) | 42 (42) | |
| Indication for neuroimaging, n (%) | 0.08c | ||
| Altered mental status | 1 (17) | 47 (47) | |
| Trauma | 1 (17) | 24 (24) | |
| Stroke symptoms | 4 (67) | 14 (14) | |
| Headache | 0 (0) | 7 (7) | |
| Seizure | 0 (0) | 3 (3) | |
| Syncope | 0 (0) | 3 (3) | |
| Dizziness | 0 (0) | 1 (1) | |
| Comorbidities, n (%) | |||
| Current smoker | 0 (0) | 7 (7) | >0.99b |
| Ex-smoker | 1 (17) | 8 (8) | 0.42b |
| Hypertension | 3 (50) | 62 (63) | 0.67b |
| Diabetes | 2 (33) | 38 (38) | >0.99b |
| Obesity | 3 (50) | 20 (20) | 0.12b |
| COPD/asthma/OSA | 2 (33) | 18 (18) | 0.32b |
| Malignancy | 0 (0) | 11 (11) | >0.99b |
| Cardiovascular disease | 1 (17) | 11 (11) | 0.53b |
| Cerebrovascular disease | 0 (0) | 7 (7) | >0.99b |
| Requiring ICU admission, n (%) | 4 (67) | 47 (47) | 0.43b |
| With intubation | 3 (50) | 42 (42) | >0.99b |
| Discharged, n (%) | 2 (33) | 46 (46) | 0.69b |
| Deceased, n (%) | 2 (33) | 11 (11) | 0.16 |
Note:—COPD indicates chronic obstructive pulmonary disease; OSA, obstructive sleep apnea; ICU, intensive care unit.
a
Two-tailed t-test.
b
Fisher's exact test.
c
Chi-squared test.