Fig 1.

Typical MR imaging brain appearances of term-born and preterm infants, at TEA. Axial T1-(A) and T2- (B) and sagittal T1 (C)-weighted images of a term-born infant (40 weeks’ gestational age) imaged at 44 weeks PMA. Note the high-T1/low-T2 signal within the PLIC from the myelin (arrows, A and B); the complex cortical folding; small, symmetric ventricles; and the typical appearance of a normal corpus callosum (arrowheads, C). By comparison, D–F are comparable images obtained from an infant born at 25 + 2 weeks’ gestational age and imaged at 42 + 4 weeks’ PMA. This infant had no acquired focal lesions however, note the scaphocephaly, reduced cortical folding, globally thinned corpus callosum (arrowheads, F), mildly dilated ventricles, and diffuse high-T2/low-T1 signal in the white matter compared with the term infant. There is grossly normal myelination in the PLIC (arrows, D and E).