Fig 1.

Acute onset of cerebral venous thrombosis in multiple locations in a man with COVID-19 without any significant comorbidities except for mild autism spectrum disorder and Tourette syndrome. A, Axial view of a CT of the chest shows patchy multifocal peripheral and peribronchovascular airspace opacities with a combination of ground-glass and consolidation in different lobes. B, Axial view, CT of the head without contrast, shows effacement of the cerebral sulci suggestive of significant cerebral edema; hyperdensity is seen in the region of the superior sagittal sinus posteriorly (arrow), characteristic of dural venous thrombosis. C, CVT with sagittal reconstruction demonstrates extensive occlusive filling thrombus within the superior sagittal (white arrow), right transverse, and sigmoid sinuses; thrombosis extends from the torcula into the straight sinus (black arrow). There is occlusion of several cortical veins adjacent to the superior sagittal sinus as well. D, Digital subtraction angiography, lateral view, reveals significant venous congestion involving the entire right cerebral hemisphere with no visualization of the superior sagittal (white arrow), transverse, and sigmoid sinuses, with clot extension in the straight sinus (black arrow).