Table 3.
Current diagnostic criteria for Gorlin Syndrome.
Major Criteria | Multiple basal cell carcinomas (more than five in a lifetime) or basal cell carcinoma occurring at a young age (<30 years old) |
Jaw keratocysts | |
Two or more palmar/plantar pits | |
Lamellar calcifications of the falx cerebri or clear evidence of calcification in an individual younger than age of 20 years | |
First degree relative with Gorlin Syndrome | |
Minor Criteria | Childhood medulloblastoma |
Lympho-mesenteric or pleural cysts | |
Macrocephaly (>97th percentile) | |
Cleft lip/palate | |
Rib anomalies (bifid, splayed, extra ribs) or vertebral anomalies (bifid vertebrae) | |
Ocular anomalies (cataract, developmental defects, pigmentary changes of the retinal epithelium) |