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. 2020 Oct 29;10:566822. doi: 10.3389/fonc.2020.566822

Table 3.

Current diagnostic criteria for Gorlin Syndrome.

Major Criteria Multiple basal cell carcinomas (more than five in a lifetime) or basal cell carcinoma occurring at a young age (<30 years old)
Jaw keratocysts
Two or more palmar/plantar pits
Lamellar calcifications of the falx cerebri or clear evidence of calcification in an individual younger than age of 20 years
First degree relative with Gorlin Syndrome
Minor Criteria Childhood medulloblastoma
Lympho-mesenteric or pleural cysts
Macrocephaly (>97th percentile)
Cleft lip/palate
Rib anomalies (bifid, splayed, extra ribs) or vertebral anomalies (bifid vertebrae)
Ocular anomalies (cataract, developmental defects, pigmentary changes of the retinal epithelium)