Table 3.
Current diagnostic criteria for Gorlin Syndrome.
| Major Criteria | Multiple basal cell carcinomas (more than five in a lifetime) or basal cell carcinoma occurring at a young age (<30 years old) |
| Jaw keratocysts | |
| Two or more palmar/plantar pits | |
| Lamellar calcifications of the falx cerebri or clear evidence of calcification in an individual younger than age of 20 years | |
| First degree relative with Gorlin Syndrome | |
| Minor Criteria | Childhood medulloblastoma |
| Lympho-mesenteric or pleural cysts | |
| Macrocephaly (>97th percentile) | |
| Cleft lip/palate | |
| Rib anomalies (bifid, splayed, extra ribs) or vertebral anomalies (bifid vertebrae) | |
| Ocular anomalies (cataract, developmental defects, pigmentary changes of the retinal epithelium) |