Fig. 3.
Neural pattern differentiation during threat appraisal and explicit memory. Anxiety group differences in neural pattern differentiation between CS−/GS versus CS+ during threat appraisal (top) and explicit memory (bottom) attention states. Neural pattern differentiation (1 - Pearson correlation coefficient) was measured in perceptual (V1, V4, ITC; columns 1–3) and affective brain regions (amygdala, AIC, dmPFC, and vmPFC; columns 4–7). Note: CS− = non-threat-associated conditioned stimulus; CS+ = threat-associated conditioned stimulus; GS = generalization stimulus; ITC = inferior temporal cortex AIC = anterior insular cortex; dmPFC = dorsomedial prefrontal cortex; vmPFC = ventromedial prefrontal cortex.