Table 1.

Summary of demographic, clinical, and lesion-level descriptive data from the study cohort.

	Multiple sclerosis	Small vessel disease
Clinical data
Patients (n)	23	11
Age
Mean (standard deviation)	42.4 years (11.9)	52.5 years (7.63)
Female (%)	14 (60.9)	11 (100)
Race (%)
White	21 (91.3)	10 (90.9)
African American	2 (8.7)	0 (0)
Asian	0 (0)	2 (9.1)
Hispanic (%)	2 (8.7)	2 (18.2)
Disease duration
Median (P25, P75)	1.99 years (0.54, 5.94)	–
Median Lesion Number (P25, P75)	11 (6.5, 14.5)	14 (12, 17)
Lesion-level data
Lesions analyzed (n)	248	157
Duration between MRI studies
Median (P25, P75)	1.65 years (1.26, 1.91)	2.74 years (1.72, 3.46)
Change in volume between MRI time points
Median (P25, P75)	− 2.32 mm3 (− 9.67, 3.48)	3.94 mm3 (− 0.65, 10.1)
Change in surface area between MRI time points
Median (P25, P75)	− 2.16 mm2 (− 8.19, 3.51)	4.18 mm2 (− 0.63, 8.93)
Theoretical Radius MRI Time Point 1 (Rij1)
Median ((Rij1 − 1) $\times$ 100) (P25, P75)	3.38 (2.41, 4.63)	2.17 (1.54, 2.81)
Theoretical Radius MRI Time Point 2 (Rij2)
Median ((Rij2 − 1) $\times$ 100) (P25, P75)	3.46 (2.48, 4.60)	2.10 (1.52, 3.06)
Displacement
Median (P25, P75)	0.39 mm (0.28, 0.56)	0.32 mm (0.22, 0.42)