Table 1.
Clinical outcomes.
| Subject | Diagnosis | Y-BOCS | HAM-D | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 6 Months | 12 Months | % Change | Baseline | 6 Months | 12 Months | % Change | ||
| 1 | OCD | 39 | 21a | 18a | −54 | 25 | 12 | 9 | −64 |
| 2 | OCD | 30 | 27 | 19a | −37 | 8 | 10 | 7 | −12.5 |
| 3 | OCD | 39 | 29 | 20a | −49 | 22 | 18 | 16 | −27 |
| 4 | OCD | 29 | 23 | 23 | −21 | 21 | 23 | 16 | −24 |
| 5 | OCD | 40 | 39 | 36 | −10 | 28 | 28 | 26 | −7 |
| 6 | MDD | – | – | – | 25 | 19 | 3a | −88 | |
| 7 | MDD | – | – | – | 23 | 19 | 25 | +9 | |
| 8 | MDD | – | – | – | 21 | 26 | 28 | +33 | |
| 9 | MDD | – | – | – | 25 | 26 | 25 | 0 | |
| 10 | MDD | – | – | – | 21 | 27 | 30 | +43 | |
OCD obsessive compulsvie disorder, MDD major depressive disorder, Y-BOCS Yale-Brown Obsessive Compulsive Scale, HAM-D 17-item Hamilton Depression Rating Scale, % Change denotes change from baseline to 12 months, negative scores represent a decrease in symptoms postoperatively, whereas positive scores represent an increase in symptoms postoperatively.
aIndicates that the subject met responder status as defined by ≥ 35% improvement on the Y-BOCS for patients with OCD and ≥ 50% improvement on the HAM-D for patients with MDD).