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. 2020 Nov 11;10:19566. doi: 10.1038/s41598-020-76140-z

Table 1.

Compounds identified as secoiridoid glycosides with key positive and negative mode neutral losses and putative assignments included.

Compound (pos*)
Rt/min
[M+Na]+
m/z
[M-H]
m/z
Molecular formula Fragments of [M + Na]+ Fragments of [M–H] Assignment References
– 162 –194 –232 –264 –386
Iridoid glycoside standards
7 1.2 413.1057 389.1089 C16H22O11 Y Monotropein standard
8* 12.6 399.1256 375.1297 C16H24O10 Y Loganic acid standard
9 14.9 709.2293 685.2349 C31H42O17 Y Y Y Y Y Nuzhenide standard
10 15.7 563.1715 539.1770 C25H32O13 Y Y Y Y Oleuropein standard
11 15.8 1095.3500 1071.3562 C48H64O27 Y Y Y Y GL3 standard
Putative iridoid glycosides in ash leaf extracts
12 12.0 443.1157 not obs C17H24O12 Y Y n/a n/a n/a 10-hydroxyoleoside 11-methyl ester 37
13* 12.4 427.1213 403.1246 C17H24O11 Y Y Oleoside methyl ester/secologanoside methyl ester 7,38
14 12.7 not obs 525.1606 C24H30O13 n/a n/a Demethyloleuropein 35,39
15 13.1 589.1729 565.1774 C23H34O16 Y Y Y Methylglucooleoside or isomer 7
16 13.3 not obs 509.1658 C24H30O12 n/a n/a Y Demethylligustroside 39
6 13.3 not obs 449.1301 C18H26O13 n/a n/a N3-hydroxytyrosol 36
1 13.5 589.1728 565.1774 C23H34O16 Y Y^ Y P2/N2 methylglucooleoside or isomer 7
17 14.8 579.1680 555.1719 C25H32O14 Y Y 10-hydroxyoleuropein 36
18 14.9 709.2311 685.2349 C31H42O17 Y Y Y Y^ Isomer of nuzhenide/excelside B 35
19 14.9 441.1376 417.1402 C18H26O11 Y Y Y Y Oleoside dimethyl ester 7,40
20 15.0 709.2323 685.2349 C31H42O17 Y Y Y Y^ Y Isomer of nuzhenide/excelside B 35
2 15.1 709.2311 685.2349 C31H42O17 Y Y Y Y^ Y Isomer of nuzhenide/excelside B 27,35
21 15.3 563.1729 539.1170 C25H32O13 Y Y Y 10-hydroxyligustroside 7
3 15.4 709.2308 685.2349 C31H42O17 Y Y Y^ Y P1/N4; isomer of nuzhenide/excelside B 27
22 15.5 1033.3161 1009.3194 C46H58O25 Y Y Y Y Y Oleoacetoside 35,4042
23 15.7 563.1725 539.1170 C25H32O13 Y Y Y Y Y Oleuropein (10) 7
24 15.9 547.1782 523.1821 C25H32O12 Y Y Y Excelsioside 7
25 16.0 741.2935 717.2975 C33H50O17 Y Y Y Y Y Isomer of jashemsloside C/D 43
26* 16.1 625.2092 601.2138 C27H38O15 Y Y Frameroside/2″-epi-frameroside 44
27 16.2 783.3401 759.3445 C36H56O17 Y Y Y Y Isomer of (9) from R. glutinosa 45
28 16.2 757.2878 733.2924 C33H50O18 Y Y^ Y Jaspofoliamoside A or isomer 41
29 16.3 933.2989 909.3034 C42H54O22 Y Y GL5 or isomer 7,8,35
30 16.3 547.1783 523.1821 C25H32O12 Y Y Y Y Ligustroside 7
31 16.7 933.3004 909.3034 C42H54O22 Y Y Y Y GL5 or isomer 7,8,35
4 17.0 933.2987 909.3034 C42H54O22 Y Y P7—GL5 or isomer 27,35
32* 17.1 967.3426 943.3453 C43H60O23 Y Y Y Isomer of pulosarioside 46
33 17.4 981.3565 957.3609 C44H62O23 Y Y Y Y Y Jaspofoliamoside E or isomer 47

*indicates compounds with significant retention time shifts (> 2 min earlier) in negative mode compared to positive ion mode due to different mobile phases.

^denotes this peak is observed but is very small; < 3% intensity of base peak.