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Genetic confirmation of C6 deficiency and hemolytic analyses of total complement activity in serum. (a) PVG H-C6-D rats showed complete loss of terminal complement activity compared to H-PVG WT (n = 8/group). (b) Genotypic results of PVG females showing genotypes F2-C6-D: 150 bp, F2–C6 WT: 200 bp, F2-C6 Het: 200 bp and 150 bp. Data points represent group means ± SEM. The original gel is provided in Supplementary Information S1.
