Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 11;10:19500. doi: 10.1038/s41598-020-76441-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

F2-C6-D PVG rats demonstrated reduced locomotor recovery compared to F2-C6 WT PVG rats. (a) Comparison of BBB scores showed that H-C6-deficient rats exhibited improved functional recovery throughout the duration of the study compared to H-C6 WT PVG rats (two way repeated measures ANOVA, *p < 0.05). Post hoc tests revealed a significant group difference 42 days post injury (Bonferroni’s multiple comparisons, *p < 0.05). (b) Comparison of BBB scores showed that F2-C6-deficient rats exhibited impaired functional recovery throughout the duration of the study compared to F2-C6 WT PVG rats (two way repeated measures ANOVA, *p = 0.0006). Post hoc tests revealed a significant group difference 42 days post injury (Bonferroni’s multiple comparisons post-hoc at day 42, **p < 0.01). (c) Terminal behavioral assessment (42 days post injury) on the horizontal ladderbeam task demonstrated that H-C6-D rats made significantly fewer errors compared to H-C6 WT (Student’s t test, #p < 0.05). (d) When comparing F2-C6-D rats performed no different from F2-C6 WT in ladderbeam errors. However there was a strong trend for F2-C6-D rats having more errors (Student’s t test, p = 0.09). Data points represent group means ± SEM.