Table 2.
Correlation between collagen triple helix repeat containing 1 (CTHRC1) immunoreactivity and clinical parameters in gastric cancer tissues
| Cases (n = 116) | CTHRC1 | CTHRC1 | P‐value | |
|---|---|---|---|---|
| Positive n (%) | Negative n (%) | |||
| Differentiation | ||||
| Well or moderate | 50 | 36 (72.0) | 14 (28.0) | 0.34 |
| Poor (or no differentiation) | 66 | 42 (78.0) | 24 (38.0) | |
| Lauren type | ||||
| Diffuse | 47 | 27 (57.4) | 20 (42.6) | 0.80 |
| Intestinal | 69 | 38 (55.1) | 31 (44.9) | |
| Depth of invasion | ||||
| T1/T2 | 70 | 42 (60.0) | 28 (40.0) | 0.04 |
| T3/T4 | 46 | 36 (78.3) | 10 (21.7) | |
| Lymph node metastasis | ||||
| − | 63 | 40 (63.5) | 23 (36.5) | 0.35 |
| + | 53 | 38 (71.7) | 15 (28.3) | |
| Size (cm) | ||||
| <5 | 75 | 48 (64.0) | 27 (36.0) | 0.31 |
| ≥5 | 41 | 30 (73.1) | 11 (26.8) | |
P‐value was calculated according to the Pearson's chi‐square‐test. Bold P‐value means that a significant correlation was found between increased CTHRC1 expression and the depth of invasion.