Skip to main content
. 2012 Sep 25;103(11):1929–1937. doi: 10.1111/j.1349-7006.2012.02409.x

Figure 4.

Figure 4

Effect of SB365 on Matrigel plug assay in vivo. (A) Effect of SB365 on Matrigel plug assay in vivo. Matrigel plugs were implanted into mice with vascular endothelial growth factor (VEGF) (50 ng/mL) and/or SB365 (10 μM). The plugs were sectioned and stained with H&E. Infiltrating microvessels with intact red blood cells were qualified by manual counting. **P < 0.01 compared to VEGF. (B) Endothelial cells in the plug were immunostained with the CD34. A stained plug was observed by microscopy at ×200 and ×400 magnifications.