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. 2012 Jul 24;103(10):1795–1802. doi: 10.1111/j.1349-7006.2012.02363.x

Figure 7.

Figure 7

Growth curves of PC‐9/ER3 xenograft tumors. PC‐9/ER3 xenograft model mice were treated with JSI‐124 (1 mg/kg/day) alone, erlotinib (25 mg/kg/day) alone, erlotinib in combination with JSI‐124, or vehicle alone. JSI‐124 alone did not inhibit tumor growth. Erlotinib alone did not significantly affect the tumor volume. The two‐drug combination resulted in significant tumor shrinkage compared to either drug alone (P < 0.05). Differences in tumor volume were compared using Student's t‐test. Bars, standard error.