Table 1.

Clinicopathologic factors, macrophage‐colony stimulating factor receptor (M‐CSFR) activation, macrophage‐colony stimulating factor (M‐CSF) expression, and signal transducer and activator of transcription‐3 (Stat3) activation in high grade glioma

Variable	n	M‐CSFR activation		P‐value	M‐CSF expression		P‐value	Stat3 activation		P‐value
		Low	High		Low	High		Low	High
Age, years
<60	26	15	11	P = 0.700	12	14	P = 0.760	11	15	P  = 0.025
≥60	36	19	17		18	18		6	30
Gender
Male	40	18	22	P  = 0.036	18	22	P = 0.470	8	32	P = 0.077
Female	22	16	6		12	10		9	13
M‐CSFR activation
Low	33	–	–	–	25	8	P  < 0.001	11	22	P = 0.270
High	29	–	–		3	26		6	23
M‐CSF expression
Low	30	–	–	–	–	–	–	10	20	P = 0.310
High	32	–	–		–	–		7	25
M2 macrophages
Low	25	15	10	P = 0.27	17	8	P  = 0.011	9	16	P = 0.210
High	37	17	20		13	24		8	29

Bold text indicates statistically significant results, calculated using the chi‐squared test.