Table 2.
Univariate Cox regression analysis of potential prognostic factors
| Univariate analysis | ||||
|---|---|---|---|---|
| n | Mean survial (weeks) | P‐value Log–rank | P‐value Wilcoxon | |
| Age, years | ||||
| <60 | 26 | 88 | 0.034 | 0.006 |
| ≥60 | 36 | 57 | ||
| Gender | ||||
| Male | 40 | 72 | 0.42 | 0.91 |
| Female | 22 | 65 | ||
| pM‐CSFR | ||||
| Low | 34 | 78 | 0.054 | 0.089 |
| High | 28 | 64 | ||
| M‐CSF | ||||
| Low | 33 | 72 | 0.49 | 0.57 |
| High | 29 | 65 | ||
| Stat3 activation | ||||
| Low | 17 | 124 | 0.058 | 0.22 |
| High | 45 | 85 | ||
| M2 ratio | ||||
| Low | 25 | 98 | 0.003 | 0.004 |
| High | 37 | 62 | ||
| MIB‐1 (%) | ||||
| <30 | 26 | 113 | 0.0005 | 0.0007 |
| ≥30 | 36 | 56 | ||
Bold text indicates statistically significant results. M‐CSF, macrophage‐colony stimulating factor; pM‐CSFR, phosphorylated M‐CSF receptor; MIB‐1, anti‐Ki‐67; Stat3, transducer and activator of transcription‐3.