Figure 5.

Lysis of autologous adult T‐cell leukemia/lymphoma (ATL) cells by Tax‐specific CTL. Tax301–309 peptide‐expanded cells from ATL patient 7 (left panel), Tax11–19 peptide‐expanded cells from patient 8 (middle panel) and Tax301–309‐stimulated patient 14 (right panel) were evaluated for cytotoxicity by a standard 4‐h chromium⁵¹ release assay. Lysis was restricted to human leukocyte antigen (HLA)‐A*24:02 or HLA‐A2 and Tax‐positive target cells. Each result represents three independent experiments.