Figure 7.
Tax expression in primary adult T‐cell leukemia/lymphoma (ATL) cell‐bearing NOG mice. Tax expression of ATL cells in each affected organ of NOG mice bearing primary ATL cells from patient 7 (A), 12 (B) and 13 (C) were evaluated. NOG mice with cells from patient 7 presented with large intraperitoneal tumor masses demarcated by the white dotted lines. Tax/human CD4 mRNA values of the cells from each organ are presented as bar graphs, where the value for TL‐Su was set at unity. Flow cytometric analysis of the cells from each organ determined by human CD45 and CD4 expression is presented. Columns, mean of triplicate experiments; bars, standard deviation. BM, bone marrow; U.L.D., under limit of detection.