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. 2012 Mar 14;103(5):851–859. doi: 10.1111/j.1349-7006.2012.02233.x

Figure 7.

Figure 7

MyD88 and IRAK4 are indispensable in heat shock protein (HSP)70‐mediated tumor rejection. On day 0, recipient mice were inoculated intradermally with E.G7 cells. On day 6, mice were transferred with OT‐I CD8+ T cells into the tail vein. On days 6, 8, 10, and 12, mice were vaccinated i.v. with 10 μg ovalbumin (OVA)‐HSP70. Tumor sizes were measured and the average tumor diameters were calculated with the formula: Average tumor diameter = [longest tumor diameter + shortest tumor diameter]/2. TLR, Toll‐like receptor.