Table 1.
Statistical analysis of the differential upregulation of PRMT5 in various primary and metastatic cancers using NCBI GEO datasets
| Disease | Probeset of PRMT5 | Variable | Sample number | P‐value | GSE Acc# | References |
|---|---|---|---|---|---|---|
| Lung cancer | 217786_at | Normal | 5 | 0.004* | GSE3268 | 44 |
| Disease | 5 | |||||
| Gastric cancer | AF015913_at | Normal | 8 | 0.001* | GSE2685 | 45 |
| Disease | 22 | |||||
| Bladder cancer | 217786_at | Normal | 9 | 0.000* | GSE3167 | 46 |
| Transitional cell carcinoma with CIS | 13 | |||||
| Bladder cancer | 217786_at | Normal | 9 | 0.000* | GSE3167 | 46 |
| Transitional cell carcinoma without CIS | 15 | |||||
| Colon | 217786_at | Primary | 3 | 0.006* | GSE1323 | 47 |
| Metastatic | 3 |
*Indicates the static significance of PRMT5 expression level between normal and cancerous tissues.