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. 2020 Nov 11;10:19535. doi: 10.1038/s41598-020-73214-w

Table 1.

Comparison of performance evaluation of linear SVM and k-NN classifiers (using the Euclidian distance) for metabolic receptors classification in subcutaneous adipose tissue. The labeled examples include 52 positive examples and 55 negative examples (rows 1 and 2) and 61 cytokines receptors as negative examples (row 3).

Method Negative group TP TN FP FN Sensitivity Specificity Accuracy MCC FP receptors FN receptors
1 k-NN Inferred receptors 50 55 0 2 0.96 0.96 0.98 0.96 NA TFRC
TFR2
2 SVM Inferred receptors 44 55 0 8 0.85 0.87 0.93 0.86 NA ADIPOR2
DRD4
EGFR
FGFR2
LDLR
LEPR
TFR2
TFRC
3 SVM/k-NN Cytokines receptors 42 60 1 10 0.81 0.86 0.9 0.81 TNFRSF21 ADIPOR2
ADRA2B
DRD4
EGFR
FGFR2
FGFR4
LDLR
LEPR
TFR2
TFRC