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. 2012 Aug 1;103(9):1665–1671. doi: 10.1111/j.1349-7006.2012.02359.x

Figure 4.

Figure 4

Effect of PTEN or epidermal growth factor receptor (EGFR) modulation on everolimus sensitivity. (a) MDA‐MB‐231 and BT20 cells were transfected with siRNA specific to human PTEN or nonspecific control siRNA. After 24 h, the cells were treated with the indicated concentrations of everolimus for 72 h. The results for MDA‐MB‐231 are shown. (b) MDA‐MB‐231 and MDA‐MB‐436 cells were transfected with retrovirus containing either an empty vector or an EGFRwt vector and then were treated with the indicated concentrations of everolimus for 96 h. The results for MDA‐MB‐231 are shown.