Table 3.

Pathways with most differentially expressed genes between pre‐ and post‐treatment among 285 BioCarta pathways

Pathway descriptions	No. of genes	LS P‐value	KS P‐value	Related pathways
VEGF, hypoxia, and angiogenesis	23	0.0018	0.0270	Angiogenesis
Hypoxia‐inducible factor in the cardiovascular system	26	0.0055	0.0023	Angiogenesis
Role of nicotinic acetylcholine	13	0.0075	0.1485	N/A
Melanocyte development and pigmentation pathway	14	0.0093	0.1461	N/A
Transcription regulation by methyltransferase of CARM1	20	0.0097	0.0378	N/A
Classical complement pathway	6	0.0141	0.0018	N/A
Role of Tob in T cell activation	26	0.0146	0.0097	T cell
Lectin‐induced complement pathway	6	0.0180	0.0018	N/A
Deregulation of CDK5 in Alzheimer's disease	20	0.0193	0.0054	N/A
IL‐12‐ and Stat4‐dependent signaling pathway in Th1 development	37	0.0254	0.0078	T cell
T cell receptor and CD3 complex	15	0.0283	0.0023	T cell
NOS2‐dependent IL‐12 pathway in NK cells	14	0.0350	0.0031	T cell
T cytotoxic cell surface molecules	28	0.0354	0.0072	T cell
T helper cell surface molecules	28	0.0354	0.0072	T cell
Role of MEF2D in T cell apoptosis	31	0.0358	0.0097	T cell
HIV‐induced T cell apoptosis	24	0.0442	0.0012	T cell
ADP‐ribosylation factor	38	0.0485	0.0087	N/A

CARM1, coactivator‐associated arginine methyltransferase 1; IL, interleukin; NK, natural killer; Stat4, signal transducer and activator of transcription‐4; N/A, not applicable; VEGF, vascular endothelial growth factor.