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. 2012 Feb 3;103(4):813–820. doi: 10.1111/j.1349-7006.2011.02199.x

Figure 1.

Figure 1

(A) Vasculogenic mimicry (VM) channel (black arrow) lined with tumor cells and containing red blood cells (HE staining, ×400). (B) Endothelial‐dependent vessel lined with shuttle‐like endothelium cells (red arrow) (HE staining, ×400). (C) The VM channel formed by tumor cells was negative for CD34 and the base membrane‐like structure between red blood cells and tumor cells was positive for periodic acid Schiff (PAS) (black arrow) (CD34/PAS double‐staining, ×400). (D) The endothelial‐dependent vessel was both positive for CD34 and PAS (red arrows) (CD34/PAS double‐staining, ×400). (E) Kaplan–Meier survival analysis showing that the VM‐positive patients have shorter survival time than VM‐negative patients. (F) Kaplan–Meier survival analysis showing the zinc finger E‐box binding homeobox 1 (ZEB1)‐positive patients have shorter survival time than ZEB1‐negative patients.