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Multridrug resistance protein‐1 (MRP1)‐overexpressing HL‐60 human leukemia variant HL/Ara‐CDNR and the P‐glycoprotein (P‐gp)‐expressing K562 variant K562/DNR19. (A,B) Two efflux pumps were evaluated. P‐glycoprotein expression was quantitated using flow cytometry (A); MRP1 was determined using real‐time RT‐PCR with the value of HL‐60 cells set as 1 (B). (C) CD33 positivity determined by flow cytometry.
