Table 2.

Commonly altered genes in gemtuzumab ozogamicin (GO)‐resistant HL‐60 variant human leukemia cell lines, HL/GO and HL/GO‐CSA

Upregulated				Downregulated
Gene	Ref. sequence	Fold change		Gene	Ref. sequence	Fold change
		HL/GO	HL/GO‐CSA			HL/GO	HL/GO‐CSA
G22P1	NM_001469	4.94	2.51	MAPK12	NM_002969	0.35	0.42
CCNH1	NM_001239	5.85	3.82	DDB2	NM_000107	0.37	3.82
RPS27A	NM_002954	3.26	2.45	ERCC5	NM_000123	0.35	0.47
CDK7	NM_001799	3.46	2.74	SPI1	NM_003120	0.17	0.26
GADD45A	NM_001924	4.98	5.56	PTPNS1	NM_080792	0.34	0.49
CETN2	NM_004344	2.65	3.56	FMO4	NM_002022	0.34	0.45
XRCC5	NM_021141	4.86	4.28	TNFRSF1A	NM_001065	0.32	0.43
RPA3	NM_002947	3.93	3.11	BCL6	NM_001706	0.31	0.40
HSPCB	NM_007355	2.47	3.39	CCNB2	NM_004701	0.26	0.33
PARP1	NM_001618	6.68	2.56	TIMP3	NM_000362	0.32	0.43
BAG3	NM_004281	2.53	2.34	TNFRSF14	NM_003820	0.32	0.46
CCNB1	NM_031966	9.55	3.93	PHB	NM_002634	0.36	0.41
SOCS2	NM_003877	3.60	3.25	TRIB3	NM_021158	0.27	0.37
CCND3	NM_001760	5.11	3.96	MST1	NM_020998	0.24	0.42
PPP2CA	NM_002715	3.55	3.55	SGK	NM_005627	0.37	0.46
CCNA2	NM_001237	4.33	2.58

Genes that showed ≥2‐fold change values were listed.