Table 3.
List of datasets extracted from GEO omnibus for the in silico analysis.
| Dataset ID | Tissue/sample | Study title | Samples |
|---|---|---|---|
| GSE4302 | Bronchial epithelium | Genome-Wide Profiling of Airway Epithelial Cells in Asthmatics, Smokers and Healthy Controls | 70 |
| GSE18965 | Bronchial epithelium | Decreased Fibronectin Production Significantly Contributes to Dysregulated Repair of Asthmatic Epithelium | 16 |
| GSE43696 | Bronchial epithelium | Asthma | 108 |
| GSE51392 | Bronchial epithelium | Expression Data From Airway Epithelial Cells Stimulated With Poly(I:C) From Patients With Asthma, Rhinitis, and Healthy Controls | 12 |
| GSE67472 | Bronchial epithelium | Airway Epithelial Gene Expression in Asthma Versus Healthy Controls | 105 |
| GSE64913 | Bronchial epithelium | Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma | 36 |
| GSE76227 | Bronchial epithelium | Expression Data of Bronchial Biopsies and Epithelial Brushing From Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes (U-BIOPRED) Project | 190 |
| GSE13785 | Bronchial epithelium | Novel Mediators of Eicosanoid and Epithelial Nitric Oxide Production in Asthma | 22 |
| GSE30063 | Bronchial epithelium | Epithelial Expression of Toll-like Receptor 5 is Modulated in Healthy Smokers and Smokers With Chronic Obstructive Lung Disease | 63 |
| GSE27335 | Bronchial fibroblasts | Genomic Differences Distinguish the Myofibroblast Phenotype of the Distal Lung From Airway Fibroblasts | 24 |
| GSE21369 | Whole lung | Gene Expression Profiles of Interstitial Lung Disease (ILD) Patients | 6 |
| GSE41649 | Bronchial biopsy | Comparison of Two Sets of Microarray Experiments to Define Allergic Asthma Expression Pattern | 8 |
| GSE56396 | Induced sputum | Non-invasive Analysis of the Airway Transcriptome Discriminates Clinical Phenotypes of Asthma | 112 |
| GSE41863 | Induced sputum | Sputum Gene Expression Profiling in Asthmatics | 56 |
| GSE41861 | Nasal | Upper Airway Gene Expression Is an Effective Surrogate Biomarker for Th2-Driven Inflammation in the Lower Airway | 84 |
| GSE41862 | Nasal | Nasal Scrape Gene Expression Profiling in Asthmatics | 116 |
| GSE67940 | Bronchioalveolar lavage | Asthma III | 104 |
| GSE115823 | Blood | A Network of Transcriptome Modules Demonstrates Mechanistic Pathways of Both Virus-Induced and Non-viral Asthma Exacerbations in Children [Blood] | 208 |
| GSE69683 | Blood | Expression Profiling in Blood From Subjects With Severe Asthma, Moderate Asthma, and Non-asthmatics Collected in the U-BIOPRED Study | 498 |
| GSE35571 | Blood | Gene Expression Data From 131 Human Subjects in Detroit, Michigan | 131 |
| GSE137394 | Whole blood | Genome-Wide Profiling of Allergic Asthma Peripheral Blood | 309 |
| GSE123750 | Whole blood | U-BIOPRED Blood Transcriptomics From children With Asthma or Wheeze | 216 |
| GSE31773 | PBMC | Comparison of mRNA Expression in Circulating T-Cells From Patients With Severe Asthma | 40 |
| GSE16032 | PBMC | Gene Expression Data From Severe Asthmatic Children: PBMC Profiles During Acute Exacerbation Versus Convalescence | 10 |
| GSE73482 | CD4 | Gene Expression Patterns in Allergen-Driven CD4 T Cell Responses From Human Atopics With or Without Asthma | 144 |
| Total | 2,666 |