Figure 2.

Outline of the CKI Workflow

(A) Data were extracted from multiple sources for curation, filtering, and normalization.

(B) mRNA levels and mutational hotspots were analyzed to generate DGE analyses and mutational frequencies. mRNA levels were also correlated with survival and clinical/pathological outcomes. Various statistical methods were employed, and all significant correlations were scored.

(C) Final CKI scores were generated and mapped to other data annotations for further analysis and interpretation.