Table 1.

Diagnostic criteria for anaphylaxis

Anaphylaxis is highly likely when any one of the following three criteria is fulfilled:
Criterion 1
Acute onset of an illness (minutes to several hours) with involvement of the skin and mucosal tissue
A. Respiratory compromise (e.g., dyspnea, wheeze/bronchospasm, stridor, reduced peak expiratory flow, hypoxemia)
B. Reduced BP or associated symptoms and signs of end‐organ dysfunction (e.g., hypotonia, collapse, syncope, incontinence)
Criterion 2
Two or more of the following that occur rapidly after exposure to a likely allergen for the patient
A. Involvement of the skin and mucosal tissue (e.g., generalized hives, itchy/flushed, swollen lips/tongue/uvula)
B. Respiratory compromise (e.g., dyspnea, wheeze/bronchospasm, stridor, reduced peak expiratory flow, hypoxemia)
C. Reduced BP or associated symptoms and signs (e.g. hypotonia, syncope, incontinence)
D. Persistent gastrointestinal symptoms and signs (e.g., crampy abdominal pain, vomiting)
Criterion 3
A. Systolic BP of <90 mmHg or >30% decrease from that person’s baseline (in adults)
B. Age‐specific low systolic BP (in infants and children)
<70 mmHg in infants aged from 1 month up to 1 year
Less than (70 mmHg + [2 × age]) in children aged 1–10 years
<90 mmHg in children aged 11–17 years

BP, blood pressure.