REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Pacific Orange live/dead stain	Invitrogen	L34959
Anti-human HBcAg	Abcam	#7841
Anti-human HBsAg	Raybiotech	#MD050186
Goat-anti-rabbit CF555	Sigma Aldrich	SAB46000068
Goat-anti-mouse APC	Life Technologies	AB_2536211
Goat-anti-mouse PE	Life Technologies	AB_2539848
HBs183-191 TCR-like antibody	Sastry et al., 2011	N/A
HBc18-27 TCR-like antibody	Sastry et al., 2011	N/A
Anti-human CD107a FITC	BD Biosciences	560949
Anti-human CD8 V500	BD Horizon	560774
Anti-human IFN-γ PeCy7	eBiosciences	AB_469682
Anti-human TNF-α PE	BD Bioscience	559321
HBs183-191 PE pentamer	ProImmune	WB3290-PE
HBs370 PE pentamer	ProImmune	WB4073-PE
EBV PE pentamer	ProImmune	WB2144-PE
Biological Samples
Human pathological liver tissue	Asian American Liver Centre, Gleneagles Hospital	https://www.aamg.co/liver/
Human HBV/HDV patient blood	Fonsazione IRCCS Ca’Granda Ospedale Maggiore Policlinico	https://www.policlinico.mi.it/
Human healthy blood	Health Sciences Authority	https://www.hsa.gov.sg/
Chemicals, Peptides, and Recombinant Proteins
Recombinant Human IL-2	R&D systems	202-1L-050
Anti-CD3	eBioscience	AB_468854
Ficoll-Paque PLUS	GE Healthcare	17-1440-02
BD Cytofix/Cytoperm Fixation	BD Bioscience	51-2090 KZ
Recombinant Human IFN-α2a	PBL	11100-1
Recombinant Human IFN-β	Peprotech	300-02BC
Recombinant Human IL-29/IFN-λ1	R&D systems	1598-IL-025
Critical Commercial Assays
Primeflow assay with customized probeset	Invitrogen	EB 16488
Nanostring human immunology version 2 and customized probes assay	Nanostring technologies	XT-CSO-HIM2-12
FASER PE amplification kit	Miltenyi	130-091-764
One Shot Top10 E. coli kit	Invitrogen	C404003
QIAamp minELute virus spin kit	QIAGEN	57704w
Rneasy Mini kit	QIAGEN	74004
mMESSAGE mMACHINE T7 Ultra kit	Ambion	AM1345
Nucelofactor kit	Lonza	V4XP-3024
Human serum albumin ELISA quantification kit	Bethyl Laboratories	E88-129
RNAScope Fluorescent Multiplex kit	Advanced Cell Diagnostics	320850
HBV Artus kit	QIAGEN	4506265
Quantitative HBsAg kit	Abbott Architect Platform	6C36
Experimental Models: Cell Lines
Primary human hepatocytes (Fresh)	Invitrocue	5M-000S
Primary human hepatocytes (Cryopreserved)	Lonza	HUM4012
HepG2-hNTCP cells	Laboratory of Stephan Urban	N/A
HepG2 cells	ATCC	HB-8065
Huh7-hNTCP cells	Laboratory of Camile Sureau	N/A
HepAD38 cells	Laboratory of Christoph Seeger	N/A
HBV HBc18-27 and HBs183-191 T cell clones	38	N/A
Experimental Models: Organisms/Strains
uPA/SCID/ILγR2 (USG) mice	21	N/A
Oligonucleotides
HDV forward and reverse primers	49	N/A
RNA in situ primers	34	N/A
Recombinant DNA
pSVLD-3 plasmid	Laboratory of Camile Sureau	Addgene: #29335
pT7HB2.7 plasmid		N/A
pVAC-HBs183 and -HBs370	50,51	N/A
Software and Algorithms
FACSDiva	BD Bioscience	https://www.bdbiosciences.com/en-us/instruments/research-instruments/research-software/flow-cytometry-acquisition/facsdiva-software
GraphPad Prism 8	GraphPad	https://www.graphpad.com/scientific-software/prism/
IDEAS software	Amnis	https://www.luminexcorp.com/imagestreamx-mk-ii/
Kaluza software	Beckman Coulter	https://www.beckman.com/flow-cytometry/software/kaluza
nSolver version 4.0	Nanostring techonologies	https://www.nanostring.com/products/analysis-software/nsolver