Table IV.
Aspiration, concentration, and application of the stem cells based on the source of the cells.
| Variable | Source | |||
|---|---|---|---|---|
| Bone (n = 83) |
Adipose (n = 7) |
Umbilical (n = 3) |
Overall (n = 94) |
|
| Volume of aspirate, ml * | ||||
| Number of studies | 50 | 3 | 2 | 52 |
| Mean (SD) | 103.3 (119.6) | 91.7 (72.2) | 45.0 (7.1) | 103.6 (117.9) |
| Median (IQR) | 60 (35.0 to 105.0) | 50 (50.0 to 175.0) | 45 (40 to 50) | 60 (37.5 to 115.0) |
| Min to max | 4 to 500 | 50 to 175 | 40 to 50 | 4 to 500 |
| Method of concentration, n | ||||
| Centrifuge | 46 | 2 | 1 | 48 |
| Culture | 17 | 2 | 2 | 19 |
| SECCS | 4 | 0 | 0 | 4 |
| Not reported | 20 | 3 | 1 | 25 |
| Volume of concentrated cells, ml * | ||||
| Number of studies | 36 | 0 | 1 | 36 |
| Mean (SD) | 15.1 (13.5) | NA | 4.0 (N/A) | 15.1 (13.5) |
| Median (IQR) | 10 (6.75 to 20.0) | NA | 4.0 (4.0 to 4.0) | 10 (6.75 to 20.0) |
| Min to max | 1.5 to 50 | N/A | 4.0 to 4.0 | 1.5 to 50 |
| Method of application, n | ||||
| Injection | 34 | 1 | 2 | 37 |
| Implant | 27 | 2 | 1 | 30 |
| On scaffold | 9 | 2 | 0 | 11 |
| Unreported | 9 | 0 | 0 | 10 |
Some studies reported more than one method and some studies did not report the method so the sum of the figures in the three method columns do not necessarily equal the overall.
*
For each study a range or point estimate was taken, the mean of the ranges was taken to give a point estimate for each study, these were then used to calculate the mean, median, and standard deviation.
IQR, interquartile range; NA, not applicable; SD, standard deviation; SECCS, screen-enrich-combine circulating system.