Table 1. RNA virus outbreaks resulting in death from 2000 to 2020.
| Virus family | Virus | Outbreak | Date | Location | Deaths | Reference |
|---|---|---|---|---|---|---|
| Arenaviridae | Lassa mammarenavirus | Hemorrhagic fever | 2000 | Germany, The Netherlands, UK, West Africa | 4 | WHO |
| 2012 | Nigeria | 70 | WHO | |||
| 2015–2016 | Benin, Liberia, Nigeria, Togo | 193 | WHO | |||
| 2017–present | Nigeria | 246 | WHO | |||
| Coronaviridae | MERS | MERS | 2012 –present | Worldwide | 862 | WHO |
| SARS-CoV-1 | SARS | 2002–2004 | Worldwide | 774 | WHO | |
| SARS-CoV-2 | COVID-19 | 2019–present | Worldwide | 650,000+ | WHO | |
| Filoviridae | Ebola | Sudan | 2004 | Sudan | 7 | WHO |
| Mweka epidemic | 2007 | DR Congo | 187 | WHO | ||
| Uganda | 2007 | Uganda | 37 | WHO | ||
| West Africa epidemic | 2013–16 | Worldwide | 11,325 | CDC/WHO | ||
| Kivu epidemic | 2018–present | DR Congo, Uganda | 2,262 | WHO | ||
| Flaviviridae | Chikungunya | 2013–15 | Americas | 1,310+ | CDC/WHO | |
| Dengue | Central America | 2000 | Central America | 37 | PAHO/WHO | |
| 2004 | Indonesia | 658 | WHO | |||
| 2005 | Singapore | 27 | WHO | |||
| 2006 | India, Pakistan | 91+ | WHO | |||
| 2006–2007 | Philippines | 2,307 | GOVPH | |||
| 2007–2008 | Americas | 250 | PAHO/WHO | |||
| South Asia | 2008 | Philippines, Cambodia | 1,000+ | GOVPH/WHO | ||
| 2009 | Bolivia | 18 | PAHO/WHO | |||
| 2011 | Pakistan | 350 | WHO | |||
| 2013 | Lao PDR | 92 | OCHA | |||
| 2016 | Americas | 1,032 | PAHO/WHO | |||
| Peshawar | 2017 | Pakistan | 69 | WHO | ||
| 2019–present | Asia-Pacific, Americas | 3,930+ | PAHO/WHO | |||
| Japanese encephalitis | Gorakhpur outbreak | 2017 | India | 1,317 | WHO | |
| Yellow fever | Darfur | 2012 | Sudan | 171 | WHO | |
| Angola | 2016 | Angola, DR Congo, China, Kenya | 100+ | WHO | ||
| Zika | 2015–16 | Worldwide | 53 | CDC/PAHO/WHO | ||
| 2020 | Brazil | 1 | PAHO | |||
| Hepeviridae | Hepatitis E | Kitgum District outbreak | 2007–2009 | Uganda | 160 | WHO |
| Maban County outbreak | 2012–2013 | Sudan | 88 | WHO | ||
| Biratnagar | 2014 | Nepal | 9 | WHO | ||
| 2019 | Namibia | 56 | WHO | |||
| Orthomyxoviridae | Influenza | H5N1 “avian” flu | 2003–present | Southeast Asia, Egypt | 455 | WHO |
| H1N1/9 “swine” flu | 2009–10 | Worldwide | 151,700–575,400 | CDC/WHO | ||
| H7N9 “avian” flu | 2013–present | China, Malaysia, Canada | 616 | FAO | ||
| H1N1 “swine” flu | 2015 | India | 2,035 | WHO | ||
| Seasonal | 2017–18 | USA | 45,000–90,000 | CDC | ||
| Paramyxoviridae | Measles | 2010–14 | DR Congo | 4,500+ | WHO | |
| 2013–14 | Vietnam | 142 | WHO | |||
| 2019–present | DR Congo | 6,400+ | WHO | |||
| Pacific Island countries and areas | 2019–present | Samoa | 83 | WHO | ||
| Nipah virus | Outbreak in Keral | 2018 | India | 17 | WHO | |
| Picornaviridae | Hepatitis A | Multistate outbreak in USA | 2016–present | USA | 332 | CDC |
CDC, Centers for Disease Control and Prevention; DR Congo, Democratic Republic of the Congo; FAO, Food and Agriculture Organization of the United States; GOVPH, Philippines Department of Health; Lao PDR, Lao People's Democratic Republic; OCHA, United Nations Office for the Coordination of Humanitarian Affairs; PAHO, Pan American Health Organization; UK, United Kingdom; USA, United States of America.