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. 2020 Aug 17;219(10):e201906023. doi: 10.1083/jcb.201906023

Figure 5.

Figure 5.

Inp1 plays a key role in peroxisome retention. (A) Single focal plane FM images of WT, inp1, pex32, and inp1 pex32 cells producing Pex3-mKate2, grown for 4 h in glucose-containing medium. (B) Quantitative analysis of peroxisome inheritance in the indicated strains. Peroxisomes from 2 × 20 cells were counted from two independent experiments. Error bars represent SD. (C) Hypothetical model showing Inp1-dependent peroxisome–PM contacts and peroxisome–ER contacts that require the Pex23 family proteins Pex32 and Pex24. Inp1 is recruited to the peroxisome by the PMP Pex3 and associates to the PM and a yet unknown PM protein (indicated with the question mark).