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. Author manuscript; available in PMC: 2020 Nov 12.
Published in final edited form as: Mol Cell. 2013 Aug 22;51(4):480–492. doi: 10.1016/j.molcel.2013.08.009

Figure 5.

Figure 5

TBP depends on TFIIA but not HLB factors, TFIIB or TFIID for binding to the histone locus. (A) Representative co-staining of TBP (green) with Lsm11 (red) in S2 cells after dsRNA treatment. From first to last row, cells after dsRNA treatment against control, Lsm11, Mxc, TFIIA-L, TFIIB, TAF4. (B) Fraction of TBP dots at His-C showing co-localization with a Lsm11 signal in cells depleted of Lsm11 or Mxc. Average of 2-3 RNAi experiments with standard deviations (N=96-169). (C) Fraction of Lsm11 dots at His-C showing co-localization with a TBP signal in cells depleted of TFIIA-L. Average of 2-3 RNAi experiments with standard deviations.