Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TBP and TFIIA are required for Pol II transcription of the His genes. (A) Unsynchronized S2 cells were stained for Pol II P-Ser5 (green) and MPM2 (red) after treatment with dsRNA for knock down of TBP, TFIIA-L, TFIIB, and TAF4. Upper panel shows representative pictures. (B) Fraction of MPM-2 dot that co-localized with Pol II signal dots after depletion of different PIC components. Average of 2-3 RNAi experiments (N=72-103, 26 for TFIIB).
