Table 7.
Linear regression analysis of relationship between the phthalate metabolites and sex and thyroid hormones in cord blood.
| Phthalate Metabolites | Female (E2) | Male (E2) | Female (TSH) | Male (TSH) | ||||
|---|---|---|---|---|---|---|---|---|
| β (95%CI) | p | β (95%CI) | p | β (95%CI) | p | β (95%CI) | p | |
| MMP | 0.007 (−0.025, 0.039) | 0.668 | 0.044 (0.001, 0.086) | 0.044 | −0.036 (−0.069, 0.003) | 0.033 | −0.017 (−0.069, 0.035) | 0.520 |
| MEP | 0.008 (−0.040, 0.055) | 0.749 | 0.023 (−0.025, 0.071) | 0.340 | −0.011 (−0.060, 0.039) | 0.673 | 0.063 (0.007, 0.120) | 0.029 |
| MnBP | 0.007 (−0.015, 0.029) | 0.538 | 0.026 (−0.027, 0.080) | 0.333 | −0.018 (−0.041, 0.004) | 0.112 | −0.011 (−0.076, 0.053) | 0.728 |
| MiBP | 0.010 (−0.011, 0.031) | 0.329 | 0.046 (0.004, 0.088) | 0.031 | −0.018 (−0.039, 0.004) | 0.111 | −0.005 (−0.056, 0.047) | 0.860 |
| MEHP | 0.007 (−0.008, 0.022) | 0.363 | −0.005 (−0.037, 0.027) | 0.759 | −0.013 (−0.028, 0.002) | 0.097 | −0.034 (−0.072, 0.004) | 0.075 |
| MEOHP | 0.002 (−0.022, 0.027) | 0.843 | 0.021 (−0.003, 0.046) | 0.081 | 0.020 (−0.006, 0.046) | 0.123 | 0.007 (−0.023, 0.036) | 0.654 |
| MECPP | −0.004 (−0.022, 0.013) | 0.636 | 0.008 (−0.011, 0.026) | 0.413 | 0.009 (−0.009, 0.028) | 0.321 | −0.006 (−0.029, 0.016) | 0.577 |
| MEHHP | −0.001 (−0.026, 0.023) | 0.921 | 0.016 (−0.006, 0.038) | 0.159 | −0.017 (−0.043, 0.008) | 0.179 | 0.015 (−0.011, 0.042) | 0.250 |
| MCMHP | −0.003 (−0.019, 0.014) | 0.748 | 0.012 (−0.008, 0.031) | 0.238 | −0.004 (−0.022, 0.013) | 0.625 | −0.012 (−0.036, 0.011) | 0.291 |
E2: estradiol; TSH: thyroid stimulating hormone. Models were adjusted for covariates including mother’s age, gestational age, pre-pregnancy BMI and GDM status. Bold italic: p < 0.05.